WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Rahaf Dayoub and Oday Jouni

ABSTRACT

Background: Intraventricular hemorrhage (IVH) remains a common and severe complication in premature infants with poor outcome, especially in severe cases. Objective: The aim of this study is to evaluate the risk factors that associated with occurrence of IVH. Materials and Methods: An observational prospective cohort study was conducted for the period two years (2020 and 2021) at Tishreen University Hospital in Lattakia-Syria. The study included two groups of premature neonates were compared: group I consisted of 31 neonates with a diagnosis of IVH(cases), whereas group II consisted of 84 neonates without IVH(controls). Results: The results showed that 26.95% of the study population had IVH, including 42% 0f mild grade and 58% of severe grade. IVH occurred during 72 hours after birth in 71% and after 3 days in 29%. The prevalence of IVH was increased significantly with decreasing of gestational age (p:0.006), birth weight (p:0.0001), Apgar score(p:0.0001), and non- using corticosteroid in the perinatal period (p:0.007). Post-natal factors that associated significantly with IVH were: need for mechanical ventilation, pneumothorax, hyaline membrane disease, PDA, hyperglycemia, acidosis, using of inotropic drugs, and septicemia(p