WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , 

ISSN 2457-0400

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Indexing

  Indexing

  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
  • IFSIJ Measure of Journal Quality
  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
  • Scholar Article Journal Index (SAJI)
  • International Scientific Indexing ( ISI )
  • Academia
  • Scope Database

Abstract

THE SENSITIVITY AND SPECIFICITY OF THE LDH LEVELS IN THE CEREBROSPINAL FLUID IN THE DIAGNOSIS OF BACTERIAL MENINGITIS IN CHILDREN

*Marah Mansour, Mazen Ghalia and Youssef Zreik

ABSTRACT

Background: Making a differential diagnosis between bacterial meningitis and aseptic meningitis is an important clinical problem. Standard routine analysis of CSF does not always provide rapid definitive information as for as causative agent is concerned. Therefore, there is a need for an additional test of CSF. Objective: The study aims to determine the sensitivity and specificity of the LDH enzyme in CSF in the early diagnosis of bacterial meningitis. Methods: In a cross-sectional study design included 90 patients with a probability of meningitis aged between one day to 12 years. Complete blood cells (CBC), C-reactive protein (Crp) were measured. Lumbar puncture was done in all stable cases and CSF was collected in sterile bottles. Analysis of the sample done in Tishreen University Laboratory. CSF LDH was done. Results: LDH levels were significantly high in bacterial meningitis and marginally raised in viral meningitis. The sensitivity of LDH enzyme in Cerebrospinal fluid in early diagnosis of bacterial meningitis was 97.22% and specificity was 86.20%. Conclusion: To conclude, LDH can be used alongside other routine tests to support the diagnosis of Meningitis and its differentiation from other types.

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