WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Logain Roumieh, Soha Asaad, Usama Alanan* and Zuheir Alshehabi

ABSTRACT

Background: Cancer is the second leading cause of. In many developing countries, the incidence of cancer appears to be much lower. Most patients are treated with a combination of surgery-radiology and/ Or chemotherapy, while in most cases the primary tumor is effectively treated with a combination of these standard treatments. Cancer immunotherapy is the use of the immune system to treat cancer. Immunotherapy is often divided into active, inactive or compound immunotherapy. This treatment highlights the fact that cancer cells often have slightly different molecules on their surface than normal cells that can be detected by the immune system. The aim of this research is to make a narrative revision on the topic of cancer immunotherapy from its beginnings to even its development with its various types and categories. Materials and Methods: Many articles and scientific researches dealing with the topic of cancer immunotherapy have been referenced. New ideas in those researches have been approached and the ideas that support the importance of immunotherapy have been arranged, as well as the challenges facing the application of this type of treatment in the treatment of cancer. Discussion: These immune cells can be reactivated and stimulated by inhibiting PD-1/PD-L1 resulting in the recognition and killing of cancer cells. However, not all cancers present appropriate immune antigens that can be effectively recognized by autologous T cells. Synthetic immune responses are the result of treatments that artificially link T cells to cancer cells that do not normally do so based on the T cell's binding to the histocompatibility complex. Conclusion: Immunotherapy is a long way of hope for the ability to treat different types of cancer, and this is still subject to continued researches in this field.

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