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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
Best Article of current issue
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PRIMARY CANCER OF THE SCROTUM IN PORT HARCOURT, NIGERIA; NATURAL HISTORY, LITERATURE REVIEW AND PROSPECTS FOR PREVENTION
Sapira, Monday Komene, MB., BS, FWACS, FMCS(Nig), FICS. and Sapira-Ordu, Leesi. MB, BS, FWACS (O&G)
Introduction: Advanced primary scrotal cancer has poor prognosis. The objective of this study is to detect and employ any favourable aspects of the natural history of the disease to prevent it and improve early presentation for treatment by affected patients. Materials and Methods: Using a common proforma, each of consecutive urology patients treated at the hospital from 01/4/2004 to 30/6/2020, was evaluated clinically with relevant investigations. History, features and chronological changes in pre-existing scrotal lesions were documented. Data were collected contemporaneously. Using search terms, the PubMed/Medline computerized data base and texts were searched for publications made on primary cancer of the scrotum during the study period. These were reviewed and relevant data obtained. Results: Of 5250 consultations, four patients had scrotal squamous cell carcinoma, and another scrotal eccrine porocarcinoma. Their ages ranged from 59 to 70 years. Duration of pre-existing scrotal lesions( in months) were 120, 24, 10, 12, and,16 respectively. Time each patient first noticed his scrotal lesion(s) to the time of histological diagnosis of malignancy (in months) were 121,25,11,13, and 17 respectively. Most premalignant or pre-existent scrotal lesions were reported to be amenable to curative preventive excisional treatment. Typical natural history of common variants of the disease characterized by slow progression from benign lesion(s) to malignancy was noted. Conclusion: We recommend informed regular preventive scrotal self-examination (RPSSE) from adolescence, excision biopsy and histology of detected scrotal lesions, and active surveillance of affected patients by clinicians.[Full Text Article]