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Best Paper Awards
World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
Best Article of current issue
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CENTRAL NERVOUS SYSTEM RELAPSE IN CHILDREN WITH ACUTE LEUKEMIA
*Dr. Nada Shakir Mahmood, Dr. Rafah Ahmed Shareef and Dr. Wallaa Abedlhaq Mahmood
During 12 years, eight hundred and seventy patient with acute leukemia were treated and seen for follow up Central Teaching Hospital for children to study the incidence of CNS relapse and the relationship between CNS relapse with some prognostic factors, the ages of patients between 5 months and 15 years, the result shows the percentage of CNS relapse was 26.55% which include ALL and AML the percentage of relapse in ALL 29.8% & AML 11.18%. and the relapse more in male than female. Among the factors influencing the increase in incidence of CNS relapse are sex (male), high initial WBC count >10000/mm3, initial organomegaly and low initial platelets count <100 000/mm3. Also the result show the more relapse occur in first year of diagnosis 72.29% and also there is recurrence of CNS relapse and more in 3-6 months between first and second relapse. Also the prognosis of CNS relapse is poor and most of them die or loss of follow up during first year after relapse.[Full Text Article]