WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals
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Indexing

Abstract

ANALYSIS OF EFFICACY OF INTRAOPERATIVE TRIAMCINOLONE ACETONIDE INJECTION WHEN COMBINED WITH SURGICAL EXCISION IN PREVENTING RECURRENCE OF KELOID

Dr. Sreelakshmi J., *Dr. Ajith P. S., Dr. Jacob Kurian, Dr. Praveen N.

ABSTRACT

Objectives 1. Primary objective of the study is to determine recurrence rate of keloid among patients who underwent surgical excision along with intraoperative administration of triamcinolone acetonide injection along wound margin. 2. Secondary objective is to assess various demographic factors involved in recurrence and subjective improvement in symptoms. Materials and Methods: Study was a Retrospective Descriptive Study and conducted among patients in whom surgical excision was combined with intraoperative triamcinolone acetonide injection for treatment for keloid. Data collected from records available in the department and interviewing patients over phone for symptoms and signs at the site of excised lesion. Recurrence and no recurrence were determined based on information provided by patient during interview. Results: In our study, 8/12(66.7%) patients had no recurrence and 4/12(33.3%) had recurrence when surgical excision was combined with intraoperative injection of triamcinolone acetonide. A curious finding, due to unknown reason, was that 5 out of 6 females (83%) with earlobe keloid had no recurrence, and remaining one had recurrence, but about 50% size compared to initial size, whereas only1 out of 3 male (33%) patients with keloid on ear had no recurrence. All patients had no itching or pain at the site after minimum 1 year of the procedure. All patients had no wound complications due to inclusion of steroid injection. Conclusion: Combining intraoperative triamcinolone acetonide injection along with surgical excision is an effective, easy, and cost-effective method in reducing keloid recurrence.

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