WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , 

ISSN 2457-0400

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Indexing

  Indexing

  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
  • IFSIJ Measure of Journal Quality
  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
  • Scholar Article Journal Index (SAJI)
  • International Scientific Indexing ( ISI )
  • Academia
  • Scope Database

Abstract

SUCCESSFUL TREATMENT OF INVAZIVE MUCORMYCOSIS FOLLOWING CHEMOTHERAPY IN A PATIENT WITH CHRONIC LYMPHOCYTIC LEUKEMIA

Dr. Abdulkerim Yıldız*, Murat Albayrak, Osman Şahin, Güleser Saylam, Gürsel Güneş, F. Aybala Altay

ABSTRACT

Mucormycosis is a fungal infection mainly affects immunocompromised patients especially with malignant hematologic diseases. Fludarabine is commonly used chemotherapeutic agent in Chronic Lymhocytic Leukemia (CLL) which causes severe immunosupression and has been suggested to increase risk of invasive fungal infections. A 70-year old man with CLL developed severe mucormycosis after the first cycle of Fludarabine-Cyclophosphamide chemotherapy. He was treated successfully with extensive surgical debridement and intravenous liposomal Amphotericin-B. This case highlighted that fludarabinebased regimens can cause severe immunosuppression and fungal infections even after first cycle of chemotherapy.

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