WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Indexing

Abstract

DEXAMETHASONE(DEX) AND PARACETAMOL SUPPOSITORY VERSUS PARACETAMOL SUPPOSITORY ON POSTOPERATIVE PAIN, NAUSEA AND VOMITING AFTER PEDIATRIC ADENOTONSILLECTOMY

Dr. Tariq Mohammd Waffek*

ABSTRACT

Background: Tonsillectomy is one of the most common surgeries in children and post tonsillectomy pain and agitation management is a great challenge for anesthesiologists. Objectives: The aim of this study was to compare the efficacy of use dexamethasone parentally. We evaluated the effect of 0.15 (0.5 mg\ kg) DEX, and Paracetamol suppository(15 mg/kg) with Paracetamol suppository(15 mg/kg) alone on the incidence of postoperative nausea and vomiting (PONV) and on pain intensity After Pediatric Adenotonsillectomy. Materials and Methods: In this study, the subjects were randomly allocated into the two groups: first group used the dexamethasone(DEX) parentally with rectally Paracetamol suppository (15 mg/kg). and second group used rectally Paracetamol suppository (15 mg/kg) only. Was started 15 minutes before the end of surgery in both groups,. Using the children’s hospital of eastern Ontario (CHEOPS) pain scale, pain and agitation score and also the incidence of nausea and vomiting after the surgery were recorded in 30 min, 3 and 10 hours after the operation. P value less than 0.03 was considered as statistically significant in all cases. Results: There was no significant difference between the two groups considering demographic data (age, sex distribution, weight and height). The CHEOPS pain scales were significantly lower in the DEX group compared to the control group at 30 minute and 3 hours after the surgery (P =0.003 and P = 0.023, respectively). There was no significant difference in the CHEOPS scale at 10 hours after the surgery, dose of adjuvant analgesic and the incidence of nausea and vomiting after the surgery between the two groups. Conclusions: According to the results of the current study, postoperative analgesia in children was improved in the DEX group. Therefore, for better management of posttonsillectomy pain, use DEX administration with Paracetamol suppository is recommended.

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