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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
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Abstract
A RARE CAUSE OF HYPERCALCAEMIA
Dr. Adel Ekladious* and Agbayani Evangeline
ABSTRACT
A 50-year old female with hypercalcaemia has been diagnosed with sarcoidosis. She came with a history of anorexia and fatigue and investigations have shown extensive pulmonary fibrosis, lytic lesions on the skull and hips, along with hypercalcaemia, hypercalciuria, nephrocalcinosis and elevated 1,25 dihydroxyvitamin D levels. Both CT guided biopsy of the mediastinal lymph nodes and bronchial biopsy and washings confirmed non-caseating granulomas which is a hallmark of but not specific to sarcoidosis. She was treated with prednisolone 30mg daily which eventually resulted into normal metabolic activity on a PET-CT scan 2 months after the initiation of treatment. Raised 1,25 dihydroxyvitamin D level is common in sarcoidosis. Measuring 1-25 hydroxyvitamin D should be a part of the workup on patients who have hypercalcaemia because it can aid in ruling out or ruling in the possibility of non-malignant granulomatous diseases.
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