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Abstract
PHARMACOKINETIC CHANGES AND PHARMACOTHERAPEUTIC APPROACHES IN SPACE ASTRONAUT
Anjum Ahamadi, Ayesha Ambereen, Mohammed Ashfaq Hussain, S. P. Srinivas Nayak*, Anupama Koneru
ABSTRACT
Space Pharmacology is the study of use of pharmaceutical drugs during spaceflights Space flight can alter administered drug act on the body. Space medicine is fundamental to the human exploration of space. It supports survival, function and performance in this challenging and potentially lethal environment. It is international, intercultural and interdisciplinary, operating at the boundaries of exploration, science, technology and medicine. This review introduces the field of space pharmacology and describes the different types of environmental challenges, associated medical and physiological effects, and medical considerations. It will describe the varied roles of the space pharmacist. Astronauts are not the only ones who benefit from space medicine research. Space pharmacology research will benefit health care on Earth. Several medical products have been developed that are space spinoffs, that is practical applications for the field of medicine arising out of the space program. It is difficult to conclude the optimal drug regimens in microgravity to ensure safe, effective, and definitive treatment of space travellers. This study is mainly focused on the health issues in space, space medicine for astronauts, pharmacokinetic, pharmacodynamics and pharmacotherapeutics in space and medicine spinoffs.
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