WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Shelly Raghav*, Yogendr Bahuguna, Chandra Shekhar Tailor, Bhawana Bhatt

ABSTRACT

During the last centuries, chemical and pharmacological studies have been performed on a lot of plant extracts to know their chemical composition and confirm the indications of traditional medicine. Phytosome plays an important role to facilitate absorption and improve bioavailability which include standardized plant extracts or water soluble phyto-constituents into phospholipids to provide lipid conformable molecular complexes. Phytosomes is a novel formulation technology which helps to overcome these problems. The term ‘phyto’ means plant while ‘some’ means cell-like. Phytosome is composed of phospholipids, mainly phosphatidylcholine, producing a lipid compatible molecular complex with other constituents. Phytosomes are more potent as compared to conventional herbal extracts owing to their enhanced capacity to cross the biological membrane and finally reaching the systemic circulation. They have anti-inflammatory, anti-oxidant, anticancer, anti-diabetic, hepato-protective properties. Phytosome has been an emerging trend in delivery of herbal drugs and nutraceuticals. This paper provides the detailed information about the preparation, advantages, characterization and evaluation of phytosomes. This review highlights information of commercial products of phytosomes as well as research on novel approaches for phytosomes drug delivery.

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