WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals
World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

ISSN 2457-0400

Impact Factor  :  5.464

News & Updation

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in WJAHR coming Issue.

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • 6th International Conference on Human and Soci

    Venue:FCT Education Resource Center, Abuja- Nigeria                                        September 22-24, 2019

  • WJAHR New Impact Factor

    Its our Pleasure to Inform you that WJAHR Impact Factor has been increased from  4.897 to 5.464 due to high quality Publication at International Level

  • .

    6th INTERNATIONAL CONFERENCE ON EDUCATIONAL TECHNOLOGY AND CURRICULUM STUDIES(ICETC2019) 

     

    Venue: FCT Education Resource Center, Abuja-Nigeria

    September 22-24, 2019

  • New Issue Published

    Its Our pleasure to inform you that, WJAHR 1 March 2021 Issue has been Published, Kindly check it on http://www.wjahr.com/home/current_issues

  • WJAHR MARCH ISSUE PUBLISHED

    MARCH 2021 Issue has been successfully launched on 1 March 2021.

Best Paper Awards

World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.

Best Article of current issue

Download Article : Click here

Indexing

Abstract

EFFECT OF ACCELERATED CORNEAL COLLAGEN CROSS-LINKING ON KERATOCONUS ENDOTHELIUM CELLS

*Hala Konz AlHaji, Taym Darwish and Kahtan Jalloul

ABSTRACT

Purpose: Evaluating the safety of Accelerated Corneal Collagen Cross-Linking on Keratoconus Endothelium cells. Methods: In this prospective study, (50) eyes of (27) progressive Keratoconus patients underwent Accelerated Corneal Collagen Cross-Linking (ACXL), (15) Epithelium-off (Epi-off) and (12) Epithelium-on (Epi-on) in the Ophthalmology Department in Tishreen University Hospital. Endothelial specular microscopy was performed on (50) eyes before, after 1, 3, and 6 months of ACXL. Studied parameters included endothelial cell density (ECD), coefficient of variation (CV) in cell area, percentage of hexagonality (EX) and corneal thickness. Results: Mean endothelial cell densities before and after six months of ACXL were 2702.6±242.2 and 2697.8±280.2, respectively (p= 0.4). Mean coefficient of variation before and after ACXL were 29.3±4.3 and 28.8±4.08 respectively (p= 0.09). Mean percentage of hexagonal cells before and after ACXL were 59.9±7.06 and 58.5±7.6 (p= 0.09), respectively. By comparing the changes of the endothelial cell parameters between the two ACXL groups, the intensity at the end of the follow-up in the Epi-off and Epi-on groups were (2781.5 ± 250.8 and 2702.8 ± 317.2), respectively (p = 0.3). The coefficient of cell volume at the end of follow-up in the Epi-off and Epi-on groups, was (29.4 ± 4.1 and 28.4 ± 4.2), respectively (p = 0.4). Average percentage of hexagonal cells at the end of follow-up in the Epi-off and Epi-on groups (57.08 ± 9.4 and 61.6 ± 5.5), respectively (p = 0.6). Corneal thickness at the end of follow-up in the Epi-off and Epi-on groups (462.2 ± 46.5 and 454.9 ± 41.7) respectively (p = 0.2). Conclusion: Accelerated Corneal Collagen Cross-Linking, including Epi-off and Epi-on, doesn't have a significant effect on corneal endothelial cells density or morphology in this study. Transient changes, that are statistically insignificant in both types, are less valuable in Epi-on ACXL.

[Full Text Article]