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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
Best Article of current issue
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ASSOCIATION OF TOTAL CHOLESTEROL, LDL AND HDL WITH CORONARY ARTERY ATHEROSCLEROSIS
Rayan Talal Sabouh*, Akram Jahjah and Youssef Zreik
Background: Atherosclerotic coronary artery disease is a major cause of death all over the world. There is a controversy about the relationship between dyslipidemia and the severity of atherosclerotic coronary artery disease in clinical and epidemiological studies. Aim: The aim of this study was to assess the relation of lipid profile and the severity of atherosclerotic coronary artery disease as assessed by coronary angiography in Syrian population. Materials and Methods: A prospective observational analytical study involved 225 individuals who underwent coronary angiography in Tishreen University Hospital, Lattakia during the period between December 2019 and December 2020. Fasting lipid profile was tested for each patient ,in addition to assessment of other coronary artery disease risk factors. Severity of CAD was determined by evaluating the number and degree of coronary artery obstructions. For statistical analysis, chi-square test and ANOVA with statistical significance set at p<0.05. Results: Dyslipidemia was found in 52.8% of patients. The most prominent lipid disorder in our study was Low HDL, which was found in 41.7% of patients. Dyslipidemia associated with the number of arteries affected by coronary atherosclerosis, but it was not an indicator of the degree of obstruction. With regard to the number of arteries affected by atherosclerosis, the statistically significant lipid disorder was high total cholesterol and high LDL. Conclusion: Dyslipidemia is a very prevalent risk factor in our patients with CAD. Low HDL was the most common lipid abnormality, while high LDL was the one that mostly related to the extent of CAD.[Full Text Article]