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RECENT TRENDS IN THE MANAGEMENT AND TREATMENT OF CANCER-A STATUS REPORT
Jayarama Reddy* and Anupama Hari
Cancer is a group of diseases characterized by unregulated cell growth, invasion into new sites and spread of cells from the site of origin to other regions of the body. According to World Health Organisation (WHO) cancer is the second leading cause of death globally. It has claimed 9.6 million lives in the world in 2019 and India‘s share in it is distressing 8.17%. India ranks third in cancer cases after China and USA. However, the American Cancer Society (ACS) reported in 2018 that cancer mortality was reduced by 1.7% which includes cancer types like, lung, breast, prostate and CRC. This may be due to steady reductions in smoking, and advances in early detection and treatment. The hallmarks of cancer include independence from growth signals, irresponsiveness to signals which halt the cell division, uncontrolled replication and evasion of apoptosis, sustained angiogenesis, and metastasis. Plethora of discoveries and growing understanding of cancer biology needs to be intelligently utilized in order to combat dreaded diseases like, cancer. In spite of accumulation of tremendous knowledge, thanks to substantial funding the incidences of full-blown malignancies have always been on the rise. Serious efforts are being made across the globe by international scientific communities to find out more and more proficient methods of curing cancer. High efficacy, lower costs and least side effects are known to be the main objectives of the researchers. Undoubtedly, conquering the warfare against cancer is and will be the focal point of contemporary medical research. This is a review of the modalities and advancements in finding an elusive yet definitive cancer treatment strategy.[Full Text Article]