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Best Paper Awards
World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
Best Article of current issue
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THE SARS-COV-2 VACCINE IS SAFE: IT IS NEITHER HARMFUL TO HUMAN CELLS NOR IT WILL INFECT HUMAN OR CAUSE DISEASE
*Mulazim Hussain Bukhari, Junu Devi and Mobeen Syed
The main objective of the vaccine is to stop transmission of SARS-CoV-2. The current vaccines (Moderna, Pfizer, Astra Zeneca, Sinoform, Sputnik-V, CanSino, Novavax etc.) have strands of genetic material called mRNA or DNA virus (viral vector) of spikes, inside a lipid Nanoparticles or adenovirus vectors. These nanoparticles coating will protect the mRNA from enzymes in the body that would otherwise break it down. It also helps the mRNA enter the dendritic cells and macrophages in the lymph node near the vaccination site and then activate the naive cells and remaining immune mechanism to develop humoral and cellular Immunity and their relevant memory cells. All the vaccines produce spike protein and not a whole virus. The mRNA vaccine induced SARS-CoV-2 immunity in all participants, and no trial-limiting safety concerns were been reported so far. It is hoped that these findings will help control the current pandemic. This is a review article based on the literature. It is to summarize the mechanism and safety of current mRNA vaccines. The authors do not have any conflict of interest.[Full Text Article]