News & Updation
Best Paper Awards
World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
Best Article of current issue
Download Article : Click here
CONTROLLING COVID-19 PANDEMIC THROUGH HORMONE CALCITRIOL
Sunil J. Wimalawansa* MD, PhD, MBA, FACP, FRCP, FRCPath, DSc
The elderly and those with underlying chronic pulmonary, cardiovascular, metabolic, and renal diseases are at a higher risk for experiencing COVID-19 infection and more prone to serious clinical complications, such as cytokine storm and acute respiratory distress syndrome, that lead to death. In addition to pulmonary cells, COVID-19 also impairs endothelial cells and could initiate intravascular haemolysis and microvascular thrombosis, and consequent pulmonary microembolization, which leads to multiorgan failure and mortality. Vitamin D adequacy could minimize the mentioned harmful outcomes. Sufficient exposure to ultraviolet B rays from sunlight and/or adequate doses of vitamin D supplements enhances the immune system. In vitro and in vivo data suggest that increase expression of anti-inflammatory, antioxidant, and antimicrobial related genes together with the suppression of excessive inflammatory and oxidative process not only minimize contracting symptomatic COVID-19 COVID infection and associated complications but also enable rapid recovery. The weaker immune system is responsible for complications and deaths from COVID-19. Administration of higher doses of vitamin D can rapidly boost the immune system. It is the most cost-effective way to keep the immune system at high alert and prevent complications and deaths from COVID-19. Therefore, a combination of safe sun exposure and oral vitamin D supplements should be used considered as a preventative measure and an adjunct therapy for managing COVID-19.[Full Text Article]