WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Indexing

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  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
  • IFSIJ Measure of Journal Quality
  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
  • Scholar Article Journal Index (SAJI)
  • International Scientific Indexing ( ISI )
  • Academia
  • Scope Database

Abstract

TOXICITY STUDIES OF VANGA BHASMA (INCINERATED FORM OF TIN) PREPARED BY TWO DIFFERENT METHODS

Dr. Jalpa Jani and Dr. Kapil Pandya*

ABSTRACT

Tin is used in a number of industrial processes throughout the world. Tinplate (sheet steel coated with a thin layer of tin) is the primary material used for food cans, and tin is also commonly used in bake ware and food storage containers. Vanga Bhasma (incinerated form of Tin) is one of the renowned Ayurvedic metallic preparations commonly prescribed by the physicians; mostly in Prameha Roga (Diabetes). In the present study Vanga Bhasma was prepared by two different methods and a comparative Acute as well as Chronic toxicity studies were done. In Acute toxicity study, up to the 2000mg/kg dose level no mortality and behavioral changes were observed. In Chronic toxicity study Ponderal changes, Bio chemical parameters, Hematological parameters and Histopathological parameters are studied. Mild fatty changes and cell infiltration was observed in Kidney and Jejunum in Charles foster albino rats at five times therapeutic Equivalent Dose.

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