WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Sweta Jangra and Debasish Chattopadhya*

ABSTRACT

Background: Coagulase negative staphylococci (CoNS) being a part of normal flora of skin, intravascular access through venepuncture may be a major point of entry for causing septicaemia. Inadequate disinfection of the venepuncture site may be responsible for rapid recolonization with CoNS that can pose risk for invasion of organism in blood leading to blood stream infections among pregnant women coming for routine antenatal check-up. Aims: Prevalence of multidrug resistant CoNS on skin at venepuncture site and analysis of various associated risk factors in antenatal care females. Material and Methods: A total of 400 antenatal females attending blood collection along with their accompanying husbands were sampled. CoNS were detected by standard bacteriological procedures, speciation was done by multiple sugar fermentation tests using commercially available kits and were subjected to AST by disc diffusion method. Results: Out of total 400 samples 260(65%) showed a positive isolation for CoNS. S.epidermidis was the most common species isolated among the CoNS isolates. The factors positively associated with CoNS carriage were milking of livestock and concomitant nasal and skin carriage of CoNS. Methicillin resistance was found among 177(68%) CoNS isolates with co-resistance towards tetracycline, erythromycin and penicillin. Few isolates were also found to be resistant to vancomycin. Conclusion: The present study suggests monitoring colonization of multi-drug resistant CoNS on venepuncture site to reduce the chances of blood stream infections among pregnant females.