WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Prajakta Kegade*, Rutuja Sawant, Shreya Parkar and Akshay Gade

ABSTRACT

Nano emulgel is the lipid based, thermodynamically stable drug delivery system.It consist of two different systems in which drug containing Nano emulsions incorporated into a gel base. The fusion of this system makes it advantageous in several ways. It is an appropriate candidate for drug delivery because of their dual character. Due to their unique property Nano-emulgel showed various applications over topically used unstable dispersions. For the enhancement of transdermal permeation, Nano-emulgel is great approach in comparison of conventional topical formulations. It also provides controlled and sustained drug delivery and have been undertaken in achieving much better drug product effectiveness, reliability and safety. Nano-emulgel is employed as a promising approach for the treatment of periodontitis. Periodontitis is a chronic inflammatory disease affecting the supporting structure of teeth. Bacteriological studies show that periodontal disease are infections caused by the overgrowth of a Gram-negative anaerobic microorganisms. The diversity of bacterial species, the variation in composition of floras and the variation in host response to bacterial species from individual to individual are some of the major reasons that the specific aetiology of periodontal disease has not been clearly established. The plaque-induced forms of periodontal diseases are the most prevalent chronic inflammatory conditions seen in humans worldwide, affecting nearly half of the adult population. Recent studies have reported that many localized deliveries of drugs such as simvastatin, ornidazole, levofloxacin have been evaluated with positive results for periodontitis.

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