WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

An International Peer Review Journal for Medical Science and Pharma Professionals
World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

ISSN 2457-0400

Impact Factor  :  5.464

News & Updation

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in WJAHR coming Issue.

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  • 6th International Conference on Human and Soci

    Venue:FCT Education Resource Center, Abuja- Nigeria                                        September 22-24, 2019

  • WJAHR New Impact Factor

    Its our Pleasure to Inform you that WJAHR Impact Factor has been increased from  4.897 to 5.464 due to high quality Publication at International Level

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    6th INTERNATIONAL CONFERENCE ON EDUCATIONAL TECHNOLOGY AND CURRICULUM STUDIES(ICETC2019) 

     

    Venue: FCT Education Resource Center, Abuja-Nigeria

    September 22-24, 2019

  • New Issue Published

    Its Our pleasure to inform you that, WJAHR 1 September 2020 Issue has been Published, Kindly check it on http://www.wjahr.com/home/current_issues

  • WJAHR SEPTEMBER ISSUE PUBLISHED

    SEPTEMBER 2020 Issue has been successfully launched on 1 September 2020.

Best Paper Awards

World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.

Best Article of current issue

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Indexing

Abstract

IN SITU GELLING SYSTEM: FOR TREATMENT OF NEUROLOGICAL DISORDERS

Shreya Parkar*, Rutuja Sawant, Prajakta Kegade and Akshay Gade

ABSTRACT

Intranasal drug delivery can be visualized as the promising route for the administration of drugs as it has the potential to overcome some major limitations associated with other routes. It is one of the promising approach for the systemic delivery of drugs because concentration time profile of drugs achieved after nasal administration is often similar to that obtained after intravenous administration. Nasal administration has a drawback of poor retention time which is overcome by novel drug delivery i.e. In-situ gelling system. In-situ gelling system is a polymeric solution which can be administered in solution form, and it undergoes sol-gel phase transition into a viscoelastic gel upon exposure to physiological conditions (e.g. pH, temperature and ionic concentration). This system also has a great impact in the treatment of neurological disorders. Neurodegenerative diseases are becoming prevalent as the population ages. Preclinical reports from several researchers have proven that the delivery to the brain via the nose-to-brain route using in situ gels holds great promise. The ‘in situ gel’ system has become one of the best novel drug delivery systems by its special characteristic feature of ‘Sol to Gel’ transition. The treatment of neurological disorders require the delivery of therapeutics to the brain in appropriate amounts to elicit a pharmacological response. Nose-to-Brain delivery has emerged as a powerful strategy to overcome the BBB and deliver drugs to the brain. The present review highlights anatomy of nose, nose to brain delivery and its advances in the treatment of neurological disorders.

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