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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
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Abstract
PREVALENCE OF THALASSEMIA TRAIT IN COUPLES TENDING FOR MARRIAGE IN NINAWA CITY
*Zakaria Abdulkhalk Abdal, Saif Waadallah Yonis and Abdulaziz Zouba Mansoor
ABSTRACT
Thalassemia is a common inherited preventable hematologic disorder by investigating hemoglobin electrophoresis. It is a worldwide disorder with a predominant incidence in Mediterranean countries, North Africa, the Middle East, India, Central Asia, and Southeast Asia. The treatment of affected individuals presents a substantial global disease burden. ?-thalassemia is characterized by the reduced synthesis (?+) or absence (?o) of the ?-goblin chains in the HbA molecule, resulting in accumulation of excess unbound ?-globin chains that precipitate in erythroid precursors in the bone marrow and in the mature erythrocytes, leading to ineffective erythropoiesis and peripheral hemolysis. Our study done on 86027 couple tending for marriage attending to official institutions health facilities In Ninawa governorate in 2019. The result was 0.44 % having thalassemia trait of couples tending for marriage. 7.7% are consanguinity relationship.
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