WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Indexing

  Indexing

  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
  • IFSIJ Measure of Journal Quality
  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
  • Scholar Article Journal Index (SAJI)
  • International Scientific Indexing ( ISI )
  • Academia
  • Scope Database

Abstract

THE PHYTOCHEMICAL CONTENT AND ANTIMICROBIAL ACTIVITY OF MUNG BEAN (VIGNA RADIATA L.) EXTRACT AGAINST SOME SELECTED PATHOGENS OF MEDICAL IMPORTANCE

Adeoye John Kayode*, Adewole Sunday Awe, Folasade Banji-Onisile, Adebanke Adeorite Agboola and Olusegun Victor Oyetayo

ABSTRACT

The current study investigated the phytochemical and antimicrobial characteristics of unsprouted mung bean seed obtained at Igasi Akoko, in Akoko North West Local Government Area of Ondo State, Nigeria. The seed (Vigna radiata L.) was grounded into powder and divided into two equal parts (A and B). Sample A was used as a positive control for bioactive components present in the seed. The crude extract of sample (B) was obtained by soaking in ethanol to extract the bioactive components. Qualitative and quantitative phytochemical analyses of samples (A) and extract of sample B were assessed. The phytochemical assay revealed that alkaloid, saponin, terpenoid, steroid, and cardiac glycosides were present, ranging from 12.47 to 47.25 mg/g and 8.05 to 27.73 mg/g respectively. The antimicrobial activity of the extract was tested against referenced microbial cultures using appropriate microbiological techniques. The antimicrobial activities of the extract vary with different zones of inhibition ranging from 2.85 to 3.10 mm against Salmonella typhi, ATCC6539 (3.05 mm) Pseudomonas aeruginosa ATCC9027 (3.10 mm) and Citrobacter freundi ATCC8090 (2.85mm) but Klebsiella pneumoniae, and Enterobacter aerogenes were resistant. The extract did not exhibit any antifungal effect against Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. In light of this finding, mung bean seed could be considered as a potential source of natural antimicrobial agent.

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