WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Indexing

Abstract

CLINICAL OUTCOMES & USE OF NEGATIVE-PRESSURE WOUND THERAPY (NPWT) IN CONTAMINATED SURGICAL WOUNDS-A REVIEW ARTICLE

Dr. Ansari Mohd. Danish Mohd. Nasim*, Dr. Huma Khatoon, Dr. Saiyad Shah Alam

ABSTRACT

Negative Pressure Wound Therapy has emerged as a pivotal advancement in the management of acute and chronic wounds, offering significant benefits in promoting granulation tissue formation, reducing edema, removing exudate, and decreasing bacterial burden. Originally inspired by ancient wound-suction practices and refined through centuries of invention, NPWT has evolved into a technologically advanced system widely used in modern surgical, traumatic, diabetic, and chronic wound care. The therapy utilizes controlled sub-atmospheric pressure delivered through foam dressings to accelerate healing and optimize the wound microenvironment. This review discusses the historical evolution, mechanism of action, clinical applications, advantages, and modern innovations of NPWT, emphasizing its effectiveness in contaminated and complex surgical wounds. Additionally, the paper highlights the integration of NPWT into long-term care settings, technological advancements, and factors influencing treatment success. NPWT continues to redefine wound care standards globally, making it an essential component of current clinical practice.

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