WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
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Abstract

THE ASSOCIATION BETWEEN SERUM ADIPONECTIN LEVEL & PRE-ECLAMPSIA

*Nadia Hasan Hussein and 2Maha Mohammed Al-Bayatti

ABSTRACT

Background: Adiponectin, a 244-amino acid protein, exhibits potent insulin-sensitizing, anti-inflammatory, and anti-atherogenic properties. However, existing literature presents conflicting evidence regarding its role in pre-eclampsia. Objective: To investigate the association between serum adiponectin levels and pre-eclampsia. Design: Case-control study. Setting: Al-Yarmouk Teaching Hospital. Methods: A total of 65 pregnant women with singleton viable fetuses in the third trimester were enrolled and categorized into three groups: 30 women with normal pregnancies, 20 women with mild pre-eclampsia, and 15 women with severe pre-eclampsia. Serum adiponectin levels were measured using the enzyme-linked immunosorbent assay (ELISA) method. Results: Serum adiponectin levels were significantly elevated in women with pre-eclampsia compared to those with normal pregnancies. The elevation was more pronounced in cases of severe pre-eclampsia. Conclusion: Adiponectin levels were markedly increased in pre-eclamptic patients, particularly in severe cases. A negative correlation was observed between adiponectin levels and blood pressure. However, no significant correlation was found between adiponectin levels and body mass index (BMI).

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