WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Mohammed Zubair Ahmed*, Pawan Kumar, Syed Azharullah Quadri, Syed Fayyazuddin,
Md. Ismail Zubair, Mohd Ateeq Ur Rehman, Mohammed Majid Iqbal

ABSTRACT

Diabetes is a serious, habitual condition that occurs when the body cannot produce enough insulin or cannot effectively use the insulin it does produce, leading to high situations of glucose (hyperglycemia). The main aim is to evaluate the safety and efficacy of anti-diabetic drugs; a prospective observational study was carried out at the department of general medicine in a tertiary care teaching hospital for a period of more than 6 months. For this study we selected the patients above 18 years of either sex, with co-morbidities, diabetes was included. It was observed that there was predominance of male 284 (56.80%), female 216 (43.20%) in the age group of 18-80 years, among that widely distributed in the age group of 51–60 years with frequency of 53%. we noted, larger numbers of patients were prescribed with metformin (16.60 %) as oral hypoglycemic agents. It was found that majority of patients were administered with regular insulin (21%) as an insulin analogue, (because of co-morbid conditions, patients were often switched to insulin therapy in comparison with the metformin). Various other combinations of oral hypoglycemic agents and insulin analogues were also prescribed. The significant risk factor was found to be age (65%) followed by sedentary lifestyle (52%) and hypertension (43%). While counselling it was recognized that the majority of patients were illiterate about the disease and counselling for the diabetes lifestyle management had a positive impact in maintaining their blood glucose levels and improved their condition. This study determined that by analyzing prescription patterns and evaluating drug-related problems, we can focus on increasing medication adherence and thereby improve patients’ health related excellence of life.