WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Abstract

ASSESSMENT OF PREMARITAL SCREENING PROGRAM OVER FIVE YEARS IN KARBALA CITY

Sumaya A. Hussein*, Prof. Dr. Ali Abdulridha Abutiheen, Dr. Muntassir K. Saod

ABSTRACT

Background: Premarital screening (PMS) is an effective preventive strategy to reduce genetic and infectious diseases by identifying carrier couples. Objective: To identify high-risk couples (carriers or confirmed cases) and estimate the prevalence of conditions included in the PMS program in Karbala over five years. Methods: A retrospective cross-sectional study included adult couples aged 18–45 years registered in five PMS clinics in Karbala governorate between 2019 and 2023. Data on hemoglobinopathies and infectious diseases were extracted from medical records and analyzed using SPSS 24. Ethical approval was obtained on 17/4/2024 from the Karbala Health Directorate Research Ethical Committee.Results: Among 102,512 individuals screened, anemia was found in 2.1% (higher in females). Thalassemia was identified in 0.9%, sickle cell anemia in 0.04%, with no sex difference. HIV cases were rare (4 total), while syphilis (44), hepatitis B (97), and hepatitis C (35) were more prevalent among males. Conclusion: The PMS program effectively identifies carriers of genetic and infectious diseases. Improved coverage, awareness campaigns, and counseling are essential to address consanguinity and early marriage.

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