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Abstract
CLINICOPATHOLOGICAL CHARACTERISTICS OF THYROID NODULES AMONG ADULT IRAQI SAMPLE
*Alaa Salim Dawood Alberta's
ABSTRACT
Background: Thyroid nodules (TNs) are estimated to affect 20% to 60% of the world's population, with rates varied by gender, age, and environment. In order to estimate the malignancy risk of nodules, specific clinicopathological characteristics such as unclear boundaries, micro-calcifications, irregular forms, solid components, and internal echoes are frequently employed.[7-8] However, it is not possible to distinguish between benign and malignant nodules with accuracy using just one characteristic. Objectives: Is to analyze the clinicopathological characteristics of thyroid nodules in a sample of Iraqi patients, as well as their available diagnostic and therapeutic options. Methods: A cross-sectional study of recorded data from the department of general surgery at Hamdanyia General Hospital, from January 2024 to the end of December 2024. The study included 50 subjects initially diagnosed with solitary thyroid nodule. Complete history and physical examination were taken from all of them as well as laboratory tests (including thyroid function tests), preoperative imaging, FNAC results, management, and final histological diagnosis. To aspirate cytological samples, a disposable plastic syringe with a 10-milliliter volume and a fine, 22-gauge needle were utilized. Results: The mean age ± standard deviation of the study participants was 36.21 ± 9.11 years. Moreover; male: female was 1:2.84. Furthermore; the majority of the patients were aged less than 30 years. In addition to that; the majority of patients had painless cervical swelling. It’s evident that the 86% of patients had normal thyroid function, followed by low thyroid function 8% and then elevated thyroid function 6%. Among females, 28 (75.67%) patients had solid mass and 9 (24.33%) patients had cystic mass. While among males, 10 (76.92%) patients had solid mass and 3 (23.08%) patients had cystic mass. lobectomy plus isthmusectomy was done for 31 (62%) patients followed by bilateral subtotal thyroidectomy for 10 (20%) patients. benign cytological findings was shown in 41 (82%) patients and colloid nodules in 40 (80%) patients. Conclusion: Higher incidence of solitary thyroid nodules is likely to occur in women and among those aged less than 40 years. Iraqi people with solitary thyroid nodules has similar clinical and epidemiological features to those from other countries. Most the patients had solid nodules and treated by lobectomy plus isthmusectomy. Most of the cytological and histopathogical results of thyroid nodules were shown to be benign and from colloid nodules.
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