WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , Research Publication Rating and Indexing , 

ISSN 2457-0400

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Indexing

Abstract

THE ROLE OF ANTICHLAMYDIA ANTIBODY IN DETECTION OF ECTOPIC PREGNANCY

*Alia Mohammad Ali and Mayyadah Mahmood Ahmed

ABSTRACT

Background: Ectopic or extra-uterine pregnancy occurs when the blastocyst implants outside of the uterinecavity's endometrium. According to several studies, a greater percentage of pregnant women with ectopicpregnancy will have serological evidence of a prior Chlamydia trachomatis infection. As infection with C.trachomatis causes the production of detectable antibodies in serum which target microorganisms, butunfortunately; there is no long-term immunity to urogenital chlamydial infections. Objectives: To compare thefrequency of Chlamydia trachomatis infection in women with ectopic and with normal pregnancy. Methods: Acase control study, carried out at Mosul and Al Hamdaniya General Hospitals (Nineveh-Iraq). The study included100 randomly selected pregnant of them 50 ladies had diagnosed first trimester tubal pregnancy (case group) andanother 50 ladies with early normal intra uterine pregnancies (after matching for age and gestational age with casegroup). The study conducted from September 1st, 2023, to March 1st, 2025. The questionnaire included two mainparts, part one for demographic and anthropometric information of the study participants, part two for the patient’santichlamydia antibody titer, part three for the diagnosis of CHD and part four for the prenatal risk factors.Results: The mean age of the study participants is 29.24 ± 5.87 years. No statistically significant differencebetween the two groups regarding their ages, residency, gravidity, parity, presence of miscarriage, gestational ageand body mass index (P value > 0.05) for all. Moreover; 42 (84%) of women with ectopic pregnancy had positiveantichalmydial antibodies while 8 (16%) of them had negative antichlamydia antibodies. Furthermore; statisticallysignificant difference was found within ectopic pregnancy group of patients regarding their age, residency,gravidity and presence of miscarriage (P value <0.001) for all of them. Lastly; statistically significant differencewas found between cases and controls regarding IgG and IgM titer (P value < 0.001) for both of them.Conclusion: Chlamydia trachomatis is clearly higher in women who have ectopic pregnancy, and it has a strongassociation with the development of ectopic pregnancy. Additionally, patients with ectopic pregnancy are morelikely to be multiparous, multigravida, and have experienced prior miscarriages.

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