WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Shakhee Mohsin Ahmed and Professor Dr. Pishtewan Hashim Saeed

ABSTRACT

Introduction: Urethral stricture refers to a fixed anatomical narrowing of the urethra that the lumen will notaccommodate instrumentation without disruption of the urethra mucosal lining. The aim of study is to evaluate theeffects of PRP injection on post internal urethrectomy stricture recurrence rate. Method: An interventional studycompares two treatment regime modalities carried out between February 2019 till November 2020. The patientwas categorized into two groups, the experimental group (13 patients) with DVIU and PRP injection and thecontrolled group (17 patients) with DVIU alone, and postoperative outcomes compared between the two groups.Result: We observed that iatrogenic trauma used to be the most common etiology of urethral stricture %43.3(experimental group %30.8 vs. comparison group %52.9 p-values 0.225). In the experimental group, 7 (%53), 5(%38.5), 2 (.4) developed hematuria, penile Pain, UTI, respectively, and stricture recurrence after 12 monthsof follow-up was 4 (%30.8). While in controlled group 6 (35.3), 3 (17.6), 1 (5.9) developed hematuria, penilePain, UT, respectively, and the recurrence rate after 12 months was %35.3. complications in the experimentalgroup were higher, but the p-value was not significant > 0.001. Conclusion: Throughout the study, we concludedthat PRP injection after DVIU is safe preparation that may decrease urethral stricture recurrence but need morescientific research to understand the long-term outcome.