WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Fatimah Ali Taha and Ahmed Jasim Muhammed

ABSTRACT

Background: Induction of labor is a method of artificially stimulating labor before spontaneous labor, with FetalFibronectin fFN being identified as a signal for term labor and delivery. Aim: To identify a parameter forpredicting successful labor induction, reduce maternal and neonatal morbidity in patients undergoing labor trials,and assist medical staff in predicting vaginal delivery. Patients and Methods: A prospective case-series studyinvolved 100 pregnant women who visited the Obstetrics and Gynecology department at Al-khansaa teachinghospital during labor. Data collection was conducted using a questionnaire form, followed by abdominal andpelvic examination. A 3-4 ml liquor sample was collected from the posterior fornix after rupture membranerupture and sent for fFN detection. Results: The correlation between Bishop Score and fetal fibronectin showed adirect but weak correlation (r=0.217) with statistically significant association (p=0.034). The ROC test for thefetal fibronectin in relation to the Bishop score revealed that the area under the curve (AUC) was 0.668 withstatistically significance (p=0.012). The statistical characteristics of fetal fibronectin showed that, at the cut-offpoint of (36.04); the sensitivity is 76.0%, while the specificity is 60.3%. Positive and negative predictive valuesare 65.6% and 71.5% respectively. Conclusion: The study found that detecting fetal fibronectin in cervicovaginalsecretions can indicate disruption of the choriodecidual interface, potentially indicating a vaginal birth deliveryroute, with a statistically significant AUC of 0.668, unlike previous studies.