WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Ali Adil Mjally*, Haider Salman Abid and Aqeel Shakir Mahmood

ABSTRACT

Background: Gastrointestinal stromal tumors (GISTs) are tumors believed to originate from the mesenchymal cells of the gastrointestinal tract. And the most common mesenchymal tumor located in the gastrointestinal (GI) tract. In very rare found extra (GI). Gastrointestinal stromal tumors were originally Surgical resection has always been a main treatment because of GISTs resistance to traditional chemotherapy and radiation. Aim of study: To reach better assessment and management of the gastrointestinal stromal tumors, with better cure rate for the patients. Methods: Between February 2022 and February 2024, 28 consecutive patients (11) women and (17) men with an age (range from 28 to 73 years) were operated on for GIST in the Department of Gastrointestinal surgery in Gastroenterology and hepatology teaching hospital and Baghdad teaching hospital medical city in Baghdad. Result: The study consists of 28 patients, male 17 (60.7%) female 11 (39.3) the age range from (28_73) years old (53.6%) more than 60 years old patients. Higher Mitotic index was also tied with larger tumors and also statistical significant (p<0.001). Tumor location most commonly found in stomach 18 cases (64.3%) followed by small bowel 5 cases (17.9%). There is statistically significant correlation between age and mitotic index (p=0.02). Higher mitotic index was correlated with younger age of the patients. Conclusion: To assess proper approach to GIST we must have MDT, to reach obtimal cure of the patients. There is strong correlation between patient age and tumor size with high mitotic index which reveal high malignancy (p=0.02 and p<0.001, respectively).