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Abstract
ALTERATIONS IN HEPATIC ENZYMES AND LIPID PROFILE IN A CROSS SECTION OF UNDERGRADUATE FEMALE STUDENTS IN NIGER DELTA UNIVERSITY HAVING STRIAE DISTENSAE
*Pughikumo D. T., Pughikumo O. C., Dowell D. Z. and Puikumo N. T.
ABSTRACT
Worrisome statistics have suggested that striae distensae (stretch mark) is high amongst young adult female in Nigeria, although undeniably, dearth of information regarding its exact relationship with biochemical indices such as lipid profile and organ functions is a gap particularly in the south southern region. Therefore this investigation sought to reduce this gap. A total of 50 young adult female aged between 18 and 25 years was divided into 2 groups of 25 each. Group 1 (test) had stretch mark and the other, group 2 (control) did not. Specified standard assay method was implored to generate relevant data which was subjected to statistical analysis with SPSS version 21. The results show significantly (p=0.025) that group 1 had higher (10.19± 2.89 mg/dl) serum total bilirubin than control (8.87± 2.40 mg/dl). Similarly, total cholesterol (14.3± 0.63 mg/dl) in serum was higher for test group than control (3.75± 0.59 mg/dl), significant at (p=0.03). Also, serum alanine aminotransferase (ALT) was higher (10.48± 2.85 mg/dl) in test group significantly (p=0.028) than control (8.88± 2.97 mg/dl). It is conceivable that these elevated levels of serum total bilirubin, ALT and total cholesterol may partly contribute in the development of this skin disorder.
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