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Abstract
THE IMPACT OF WEIGHT LOSS ON SYMPTOMS OF POLYCYSTIC OVARY SYNDROME AMONG OVERWEIGHT AND OBESE REPRODUCTIVE AGE WOMEN
*Shaymaa Hussein Ali and Muthana Abdulrazzaq Jabbar
ABSTRACT
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-age women, often associated with obesity, insulin resistance, and reproductive dysfunction. Weight loss is considered an essential management strategy to alleviate PCOS symptoms and improve metabolic and reproductive outcomes. Aim: This study aimed to evaluate the impact of weight loss on waist circumference, body mass index (BMI), and symptom improvement in overweight and obese reproductive-age women with PCOS. Method: A prospective study was conducted on 100 overweight and obese women diagnosed with PCOS. Participants were followed for 16 weeks at the gynecology and obstetrics consultation clinic at Diyala/Jalwla General Hospital. The intervention included a structured weight loss program involving dietary plans and lifestyle modifications. Changes in waist circumference and BMI were recorded, and statistical analysis was performed using paired t-tests and chi-square tests. Results: The study demonstrated a significant reduction in waist circumference (mean decrease from 100.82 cm to 93.01 cm) and BMI (mean decrease from 31.46 to 27.06), both with P-values = 0.0001. BMI reduction was significantly associated with symptom improvement (P-value = 0.002), while waist circumference showed a borderline significance (P-value = 0.05). There was no significant association between demographic factors (age, marital status, family history of PCOS) and symptom improvement. Conclusion: Weight loss, particularly BMI reduction, plays a crucial role in improving PCOS symptoms and metabolic health. This study highlights the importance of lifestyle interventions in managing PCOS and suggests that achieving a normal BMI is key to symptom improvement. Future research should explore the long-term effects of weight loss and its combination with other treatments for comprehensive PCOS management.
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