WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Ratan Kumar* and Adyasha Mishra

ABSTRACT

Dengue infection typically manifests with a course of 3 phases. Initial Febrile phase is characterized by fever, body ache, bone pain, muscle pain, and generalized weakness. Next, critical phase starts with defervescence and is characterized by bleeding and increased capillary permeability leading to third spacing of fluid and shock. Finally, stabilization of hemodynamic parameters and diuresis is seen in convalescent phase. Here, we present a series of 4 cases of dengue in children presenting differently from the typical course of illness. First case is of a 12 year 8 months old male who presented with status epilepticus on day 1 of illness. Second case is of infantile dengue, who presented with acute gastroenteritis and hypovolemic shock on day 2 of fever. Third case, 14 year 4 months old male, who presented with syncope followed by shock and acute kidney injury (AKI) stage 1. Fourth case is of 14 years old male who presented with shock on Day 1 of illness and then with hyperinflammatory response. All 4 cases required intensive care and recovered completely with appropriate and timely treatment. This case series highlights that deviation from natural course of illness in dengue is frequent in children. High index of suspicion in dengue endemic region and early diagnosis helps in improving outcome.

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