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Abstract
PHARMACOGNOSTIC PROFILE AND OF ANTI DIABETIC ACTIVITY OF CORCHORUS TRILOCULARIS
*Abhishek Mishra, Satkar Prasad and Khushboo Chauhan
ABSTRACT
Diabetes has been recognized as a major health problem worldwide for the twenty-first century. Developing countries of Asia and Africa are the most viable areas where the disease is feared to raise 2–3 folds. A survey revealed that it is expected to increase to 366 million people by 2030 worldwide In particular, the number of people with diabetes in India is around 40.9 million by 2004 and is expected to rise to 69.9 million by 2030. India leads the world with largest number of diabetic subjects thus earning the dubious distinction of being termed the ‘‘Diabetes Capital of the World”. The disease imposes huge human and economic costs on patients, their families, local communities, health care systems, and societies. Diabetes mellitus was known to ancient Indian physicians as ‘madumeha’. Diabetes mellitus (DM) is a chronic and metabolic disease affecting glucose, fat, and protein metabolism Diabetes is defined as a state in which homeostasis of carbohydrate, protein and lipid metabolism is improperly regulated as a consequence of a relative or absolute deficiency of insulin secretion, resistance to insulin action or both at one or more points in the complex pathways of hormone action. This results primarily in elevated fasting and postprandial blood glucose levels. If this imbalanced homeostasis doesn’t return to normalcy and continuous for a protracted period of time, it leads to hyperglycemia that is due course turns into a syndrome called diabetes mellitus.
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