WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , 

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Indexing

  Indexing

  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
  • IFSIJ Measure of Journal Quality
  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
  • Scholar Article Journal Index (SAJI)
  • International Scientific Indexing ( ISI )
  • Academia
  • Scope Database

Abstract

SUSTAINABLE AND GREEN APPROACHES IN NOVEL DRUG DELIVERY SYSTEMS: INNOVATIONS IN ECO-FRIENDLY DRUG DELIVERY TECHNOLOGIES

Rimmy Nandal, Anil Kumar, Narendra Sharma, Yash Dhubkaria, Konda V. V. S. Krishna, Yash Srivastav, Sanmati Kumar Jain, Manoj Kumar Katual and Uriti Sri Venkatesh*

ABSTRACT

Background: The global pharmaceutical industry is facing increasing pressure to adopt sustainable and eco-friendly practices due to growing environmental concerns. Traditional drug delivery systems (DDS) contribute to environmental challenges through the use of non-biodegradable materials, toxic solvents, and energy-intensive manufacturing processes. The emergence of green and sustainable approaches in DDS aims to mitigate these issues by incorporating biodegradable materials, green chemistry principles, and eco-friendly nanotechnology. Objective: This review focuses on recent innovations in sustainable and green drug delivery systems, exploring the integration of eco-friendly materials, energy-efficient manufacturing techniques, and green nanotechnology to reduce the environmental footprint of pharmaceutical products. Key challenges, limitations, and future directions are also examined. Methods: A systematic search was conducted across scientific databases including PubMed, Scopus, and Web of Science for articles published between 2010 and 2024. The selection criteria included studies discussing green chemistry, biodegradable materials, sustainable packaging, and eco-friendly nanotechnologies in drug delivery. Case studies of commercially implemented green DDS were also analyzed to identify successful innovations. Results: The review identified several biodegradable polymers (e.g., chitosan, PLA, and PLGA) and green solvents (e.g., supercritical fluids and ionic liquids) as sustainable alternatives to traditional materials and solvents. Green nanotechnology, particularly phytochemical-based nanoparticle synthesis, demonstrated lower environmental impact and increased drug targeting efficiency. Challenges such as regulatory barriers, higher production costs, and limited scalability remain obstacles to widespread adoption. Conclusion: Green and sustainable approaches in drug delivery offer significant potential to reduce the environmental impact of pharmaceuticals while maintaining therapeutic efficacy. Further research and development are essential to address the economic and regulatory challenges, enhance market acceptance, and scale up eco-friendly technologies for widespread application. Collaboration between industry and academia is key to driving the transition toward fully sustainable DDS.

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