WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Raghad T. Aziz, Nourhan T. Younis, Sarmad O. Rashid, Zakaria A. Kassim* and Sharef W. Mulaabed

ABSTRACT

Objectives: To evaluate the glycemic control and to identify the possible side effects of multiple insulin regimen versus twice daily regimen among patients visited to endocrine consultation unit at Al Khansa'a Teaching Hospital in Mosul during 1st of January 2023 to the end of December 2023. Methods: this is a cohort comparative study. Patients’ case sheets were reviewed to acquire the mandatory information. The questionnaire was composed of two parts, the first included demographic information of the patients and the second covered specific diabetes mellitus information. Results: Sixty-nine children with type 1 diabetes were included in the study, with (52%) males and (48%) females. Two third of the studied sample were on multiple daily injections of insulin and one third were on twice daily dosing. HbA1c mean was dropped from 10.8 ± 1.7 at baseline to 8.5 ± 1.5 (p < 0.001) in BID group, while it dropped from 11.3 ± 1.7 at baseline to 8.1 ± 1.0 (p < 0.001) in MDI group, which make MDI regimen had trend toward statistical significance in comparison to BID. There was no significant difference in reported hypoglycemia between the two groups: MDI group reported hypoglycemia in 29 out of 43 (67%) compared to 16 out of 26 (62%) in BID group. Conclusion: It has been demonstrated that multiple insulin regimen improves children and teenager’s glycemic control, we recommend ministry of health to provide rapid-acting insulin (Aspart) and long-acting insulin (glargine) in hospital and centers dealing with diabetes as its price is not affordable to all patients’ families.