WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Indexing

Abstract

GASTRITIS WITH H-PYLORI INFECTION IN RELATION WITH MUCOSAL WALL THICKENING /ANTRAL WALL THICKENING RATIO

*Dr. Ali Mahmoud Alwan Al-Saji

ABSTRACT

Background: Gastritis is a mucosal inflammation caused by H. pylori infection, autoimmune diseases, bile reflux, and alcohol. It's linked to various gastroduodenal diseases. In Iraq, H. pylori prevalence is 11.3-71.3%. Diagnosis varies based on sensitivity, specificity, and cost. Aim: To evaluate several approaches for determining the prevalence of H. pylori in Iraqi patients with the gold standard method of qPCR. Methodology: A cross-sectional study was conducted at Al-Selekh Primary Health Care Center, Al-Numaan Hospital, and Dr. Ali Al-Saji private clinic, involving 120 patients with dyspepsia. The patients were divided into two groups based on diagnosis: those diagnosed with gastritis with Helicobacter pylori diagnostic tests and those without. The patients were categorized based on their history of dyspepsia and were asked to undergo upper gastrointestinal tract endoscopy, biopsy, abdominal ultrasonography, and blood tests. The data was analyzed using IBM-SPSS 26. Results: The study involved 160 patients with gastritis, with 60 in groups A and B. The mean age was 36.71±14.599 years, with no significant difference. Males constituted 35.0% of group A and 48.3% of group B, while females were 65.0% and 51.7% respectively. Antral wall thickness was higher in group A (4.80±1.098) than group B (3.45±1.113), and mucosal wall thickness was higher in group A (2.88±0.810). Conclusion: The study found that the antral and mucosal thickness were associated with H. pylori in patients with gastritis and differed significantly from those in non H. pylori gastritis.

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