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Abstract
MUSCULOSKELETAL MANIFESTATIONS IN HEMOPHILIC PATIENTS IN IBN-SINA TEACHING HOSPITAL, IN MOSUL CITY. IRAQ. 2020
Raghad Najm Abdullah Al Nuaimi*, Khalid N. M. Al-Kheroo and Aseel Saad Tahir Maaroof
ABSTRACT
Background: Hemophilia is a coagulation disorder caused by a deficiency of coagulation factor VIII (hemophilia A) or factor IX (hemophilia B, also known as Christmas disease). Hemophilic patients can experience numerous musculoskeletal complications. Objectives: Evaluation of musculoskeletal manifestations in hemophilic patients, including clinical and radiological characteristics, and the correlation between them. Patients and Methods: A case series study was conducted on fifty male hemophilic patients aged between 4 and 50 years with moderate and severe hemophilia. The study took place in the hematology unit of Ibn-Sina teaching hospital over six months from October 2020 to March 2021. All patients underwent a thorough history taking and local physical examination of the 'target joint' using the Gilbert score. Additionally, all patients received conventional frontal and lateral radiography of the target joint at the radiology institute. Results: Chronic synovitis was present in 32 patients, acute hemarthrosis in 20 patients, deforming arthropathy in 6 patients, muscle bleeding in 5 patients, and pseudotumor in one patient. A statistically significant positive correlation was found between Gilbert's score and Pettersson's score. Conclusion: Hemophiliac patients often experience musculoskeletal complications, such as chronic synovitis, acute hemarthrosis, deforming arthropathy, muscle bleeding, and pseudotumor. The knee is the most commonly affected joint. The evaluation of joint status is crucial and can be done using the Gilbert score and Pettersson scoring system.
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