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Abstract
ASSESSMENT OF COLPOSCOPY AND HISTOPATHOLOGICAL FINDINGS IN PRECANCEROUS CERVICAL LESIONS
Wassan Shuaith Oudah Al-Aqeeli*, Lamees Adnan Shubber and Besmah M. Ali
ABSTRACT
Cervical cancer remains a major health concern worldwide, particularly in less developed regions, where it significantly contributes to cancer-related morbidity and mortality among women. Early detection and intervention are critical for managing and preventing the progression of precancerous lesions. This study evaluates the colposcopy and histopathological findings in women with precancerous cervical conditions, underscoring the importance of regular screening and early detection. Objectives: The study aims to assess colposcopy and histopathological findings in women with precancerous cervical conditions from February 1, 2024, to August 1, 2024. Methods: A cross-sectional study was conducted involving 120 married or sexually active women of reproductive age (20–70+ years) at Al Yarmoke Teaching Hospital in Baghdad, Iraq. Data was collected from the hospital's women's health center over six months. Participants underwent colposcopy and Pap smear tests, followed by cervical biopsy for those who tested positive. The data were analyzed using SPSS 22.0, with categorical data presented as frequency and percentage. Results: Colposcopy demonstrated high sensitivity (85.71%) in identifying true positive cases, indicating its effectiveness in detecting cervical abnormalities. However, its specificity was moderate (60%), suggesting a notable rate of false positives. The positive predictive value (PPV) and negative predictive value (NPV) were both 75%, reflecting a reliable confirmation of the presence and absence of disease. The overall accuracy of colposcopy was 75%. Conclusions: Colposcopy is a valuable diagnostic tool for identifying precancerous cervical lesions, with high sensitivity and moderate specificity. Its PPV and NPV of 75% indicate reliability in confirming disease status. Despite its overall accuracy of 75%, additional confirmatory tests are recommended to enhance diagnostic precision, highlighting the importance of regular screening and early detection in managing cervical cancer.
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