WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
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Abstract

IN SILICO STUDIES ON DENGUE AND HANTAAN VIRAL STRUCTURAL PROTEINS WITH SELECTED CORIANDER SATIVUM L CONSTITUENTS

Nagarjun N., Aniruddha B. S., Ashwini B. M., Mahesh K., Nagarathna Amresh and *Balasubramanian Sathyamurthy

ABSTRACT

Coriander sativum L belongs to family Umballiferae/Apiaceae. The constituents of Coriander sativum L are used as herbs in Ayurvedic medicine. They are believed to possess anti-diabetic, anti microbial, anti inflammatory properties. The GCMS results showed the presence of 7 compounds in Coriander sativum L with a wide variety of biological activities. The comparative study of Dengue and Hantaan viruses with their structural protein for dengue were carried out through In Silico methods. In this study we examined the binding affinities of 7 ligands with 4 proteins of both dengue and Hantaan viruses. By our virtual screening and molecular docking result, we found that the Compound Hexadecanoicacid, methyl ester had the highest binding affinity with these proteins.

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