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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
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Abstract
ANTI-SYNTHETASE SYNDROME: A CLINICIAN’S NIGHTMARE
Varun M. Nagaraja, *Pradeep Marur Venkategowda, Shankar V. and Himaal Dev G. J.
ABSTRACT
A 63-year-old male patient presented with complaints of generalized weakness, bilateral lower limb pain, swelling, and hyperkeratotic skin lesions. His myositis panel was positive for anti-KU and PL-12. Chest CT showed diffuse ground glass opacities with a non-specific interstitial pneumonitis pattern. This was suggestive of Anti synthetase syndrome. He was treated with Methylprednisolone for 3 days and later with Mycophenolic acid tablets. He was shifted to wards on the 9th day. On the 12th day, the patient was shifted back to the Intensive care unit (ICU) and he died due to bilateral aspiration pneumonia with multiorgan failure. The sudden deterioration of his condition could be due to rare complications such as pharyngeal paralysis and aspiration, myocarditis, or secondary infection. Diagnosing this myositis is difficult since the clinical features are so disparate and we should be aware of rare complications which can cause increased mortality.
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