WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , Research Publication Rating and Indexing , 

ISSN 2457-0400

Impact Factor  :  6.711

WJAHR Citation

  All Since 2020
 Citation  105  60
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Indexing

Abstract

ANTI-SYNTHETASE SYNDROME: A CLINICIAN’S NIGHTMARE

Varun M. Nagaraja, *Pradeep Marur Venkategowda, Shankar V. and Himaal Dev G. J.

ABSTRACT

A 63-year-old male patient presented with complaints of generalized weakness, bilateral lower limb pain, swelling, and hyperkeratotic skin lesions. His myositis panel was positive for anti-KU and PL-12. Chest CT showed diffuse ground glass opacities with a non-specific interstitial pneumonitis pattern. This was suggestive of Anti synthetase syndrome. He was treated with Methylprednisolone for 3 days and later with Mycophenolic acid tablets. He was shifted to wards on the 9th day. On the 12th day, the patient was shifted back to the Intensive care unit (ICU) and he died due to bilateral aspiration pneumonia with multiorgan failure. The sudden deterioration of his condition could be due to rare complications such as pharyngeal paralysis and aspiration, myocarditis, or secondary infection. Diagnosing this myositis is difficult since the clinical features are so disparate and we should be aware of rare complications which can cause increased mortality.

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