WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
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  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
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Abstract

UNVEILING SUBTLE MYCOBACTERIUM TUBERCULOSIS INFECTION WITH UNUSUAL RIFAMPICIN SUSCEPTIBILITY: A CASE STUDY UTILIZING XPERT MTB/RIF

A. Rakesh Reddy*, Basani Pavithra, Samreddy Bhavani, Degam Akshaya, Rasuri Charishma and Dr. Shiva Raju

ABSTRACT

Extrapulmonary tuberculosis (EPTB) poses diagnostic dilemmas due to its varied clinical presentations and the absence of classical symptoms. Here, we present the case of a 71-year-old female exhibiting intermittent fever, chills, generalized weakness, and joint pains, alongside extensive lymphadenopathy involving cervical, supraclavicular, and axillary regions. PET-CT imaging revealed metabolically active lymph nodes, prompting biopsy confirmation of Mycobacterium tuberculosis (MTB) via GeneXpert, despite negative acid-fast bacilli (AFB) testing. Notably, low MTB levels with no rifampicin resistance were detected. This case underscores the critical role of advanced diagnostic modalities, particularly GeneXpert, in identifying EPTB, especially in scenarios with low bacterial burden. Effective management, guided by precise diagnosis, ensured favourable patient outcomes.

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