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Abstract
COMPARATIVE EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF HERBAL AND UNANI FORMULATION, ON AMOXICILLIN/CLAVULANIC ACID-INDUCED LIVER INJURY IN WISTAR RATS
Aashish Kumar, Lalit Parihar, Sanjar Alam and Swamita Arora*
ABSTRACT
Liver damage is a significant global health concern, and the use of herbal remedies as a balancing and alternativeapproach to liver disorders has grown in favor. A review of liver injury and the roles played by herbal remedies inits administration, together with any potential advantages, difficulties, and future directions, are provided in thisabstract. Treatments for liver injury that are often used in medicine include immunosuppressive drugs, antiviraldrugs, lifestyle changes, and surgery. This study was undertaken to examine the hepatoprotective activity ofinducing drug amoxicillin/clavulanic acid and treatment of herbal protective drug jigreen , liv 52, and Silymarin.The hepatoprotective effects of various herbs and natural substances are combined in these formulations. It ispostulated that Liv.52 and Jigreen, given their makeup, may have antioxidant qualities following the damagecaused by amoxicillin/clavulanic acid. It is hypothesized that Liv.52 and Jigreen, due to their traditional use forliver health and the hepatoprotective qualities of their herbal components, may have antioxidant benefits. Toelucidate the underlying mechanisms and evaluate the potential clinical consequences of Jigreen and Liv.52 asantioxidants, more research is required. Extensive experimental and clinical research is required to support thistheory and provide evidence on the function of these formulations in enhancing liver health and thwartingoxidative stress.
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