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Abstract
AN OVERVIEW OF PSORIASIS: AN AUTOIMMUNE DISORDER - PREVENTION TO IT'S CLINICAL APPROACH
Sarvan, Almaz Kamran, Uriti Sri Venkatesh, Sanjeev Kumar, Rajesh M Meshram, Vishal Pathak, Yash Dhubkaria, Neha Singh and Anil Kumar*
ABSTRACT
Psoriasis causes the skin to multiply tenfold faster than usual. Red, itchy, scale-covered skin plaques are some ofthe most common symptoms. Patients with psoriasis may develop psoriatic arthritis, a kind of arthritis. Guttatepsoriasis often begins in childhood or early adulthood. Guttate psoriasis is distinguished by smooth, glossy,intense red skin regions without scales. People with psoriatic arthritis frequently develop widespread nailpsoriasis. Ninety percent of persons who have it have altered nails. Psoriasis pathogenesis involves inflammation,abnormal epidermis keratinocyte multiplication, excessive proliferation, and alterations in the skin's immunesystem. An immune response dysfunction is what causes inflammation. Psoriasis is often passed on via families,however it can occur throughout several generations. Because the immune system is compromised in psoriasis,stimuli such as cold, dry weather, and stress exacerbate symptoms. Purplish-colored patches with grey scales onvery black skin have been seen in the African American population. While there is no cure for psoriasis, therapycan considerably lessen symptoms, especially in severe situations. The physician creates a treatment plan based onthe location of the rash, age, overall health, and other considerations. Retinoids and steroids are given as creams,ointments, gels, and so forth. For people with mild to severe psoriasis, there are several therapy options available.This article provides an overview of the many kinds of psoriasis, pathogenesis, diagnosis, consequences,prevention, and potential therapies.
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