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Abstract
AN OVERVIEW AND COMPARISON OF CONVENTIONAL AND NANOTECHNOLOGY BASED ANTIVIRAL APPROACHES FOR COVID-19
*Anubhav Jain, Deepak Kumar and Dr. Parul Grover
ABSTRACT
Since the end of 2019, the whole world was introduced to a new pandemic situation called COVID -19. Thisoutbreak was named novel coronavirus (2019-nCov) by World Health Organization (WHO) and still, there is notany promising solution to tackle this pandemic disease. For diagnostic, preventive, control, and treatment ofCOVID-19, various strategies have been developed. Therefore, several antiviral agents are used against COVID-19. Antiviral agents such as M2 ion channel blockers, protease inhibitors, neuraminidase inhibitors, and fusioninhibitors are seen effective against 2019-nCov. Nowadays, many antiviral drugs used for the treatment of diseaseare available in form of nanoparticles and the antiviral based-nanoparticles prove to be a very powerful approachfor COVID-19 treatment. Many case studies showed that nanoparticles have various advantages over conventionaldosage forms such as improved efficacy and safety, etc. This review attempts to focus on the preparation andevaluation of nanotechnology-based antiviral drugs. The review includes case studies, clinical trials, and acomparison of conventional and nanotechnology-based antiviral approaches for COVID-19.
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