WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Khetam Sadiq Jaffer* and Ban Jumaah Qasim

ABSTRACT

Background: Breast cancer is the most common invasive cancer and the second leading cause of cancer deathsamong women globally, diagnosed through clinical exams, radiological imaging, and biopsy. Breast ultrasounds,favored for their safety and lack of ionizing radiation, are key in evaluating breast masses. Tru-cut biopsies arepreferred over Fine Needle Aspiration Cytology for providing ample tissue for accurate diagnosis and treatmentplanning. Objective: Compare clinico-pathological aspects of breast masses obtained by Tru-cut biopsies toultrasonography results and evaluate their validity. Method: A retrospective study spanning January 2022 toJanuary 2023 analyzed 100 breast Tru-cut biopsies from Al-Imamain Al-Kadhimain Medical City, OncologyTeaching Hospital, and private labs, focusing on histopathological reports, slides, and clinical parameters.Histopathological diagnoses and ultrasound findings were collated from reports. Additionally, H&E stained slideswere re-examined by a supervisor pathologist at Al-Nahrain University's College of Medicine for diagnosticrevision. Results: In a study sample aged 21-85 years (mean 49.9±12.5), 82% were married and multiparous, with68% presenting palpable masses predominantly in the right breast's upper outer quadrant (31%). The majority(77%) of biopsies revealed malignancy, with invasive ductal carcinoma being the most common tumor (60%).Ultrasound findings predominantly showed BIRADs IV (58%) and V (33%) classifications, indicating a highlikelihood of malignancy. Conclusion: The majority of core biopsy results were cancerous. Most cancers wereinvasive ductal carcinoma. Ultrasound was significantly associated with histopathology (tru-cut needle biopsy).Radio-pathological correlation is crucial for reliable outcomes. Tru-cut biopsy sensitivity, specificity, andaccuracy (98%, 100%, 95%).