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Best Paper Awards
World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
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Abstract
COMPARATIVE EVALUATION OF SCHIZANDRA FRUIT AND VITAMIN E ON LEARNING AND MEMORY BEHAVIOUR IN EXPERIMENTAL MODEL OF STRESSED SWISS CDI MICE
Joffa P. P. K.*, Erigbali P. P., Egbejimi A. M., Kiridi E. G. and Dabirilagha O. F.
ABSTRACT
Schizandra fruit and vitamin E were evaluated for comparative cognitive health benefits in Swiss mice. Stress was induced in rodents pre-administered with schizandra and vitamin E, within experimentally designed scope. Thereafter, they were assessed alongside non-treated control rodents with Neurobehaviour parameters (swim latency, retention quadrant duration, annulus crossings, percentage % correct entry); that depict learning and memory, using established protocols of Morris water maze and spontaneous alternation test. From the observations, treatment with schizandra (referential) and vitamin E (known standard pill) both enhanced visuospatial memory in stressed mice, with vitamin E appearing more potent. Although isolated investigation of active ingredient in schizandra may be more hopeful.
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