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Abstract
OFF-LABEL BENEFIT OF BACLOFEN: ALCOHOL USE DISORDER & ALCOHOL WITHDRAWAL SYNDROME
Dr. Azher Sharif* and Dr. Syed Bilal Yahya
ABSTRACT
Baclofen, an anti-spasmodic drug developed by Swiss chemist Heinrich Keberle, as an antiepileptic in the year1962. Although baclofen was found to be ineffective for the treatment of epilepsy, it was found effective in thetreatment of spasticity in specific patients, based upon this it was recognized and introduced as anti-spasmodic inthe year 1971 and the US Food and Drug Administration (FDA) granted approval in 1977 for the treatment ofspasticity associated with multiple sclerosis, spinal cord injuries, and other spinal cord pathologies.[1]
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