WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*1Dr. R. Anil Kumar and 2Dr. Surekha B. Shetty

ABSTRACT

Reactive hypoglycemia (RH) is the condition of postprandial hypoglycemia occurring 2-5 hours after foodintake.[1] It is clinically seen in three different forms as follows.1. Idiopathic reactive hypoglycemia. (at 180 min)2. Alimentary reactive hypoglycemia. (within 120 min)3. Late reactive hypoglycemia (240–300 min)The symptoms of reactive hypoglycemia generally start within 4 hours after a meal. They can include anxiety, blurryvision, racing heart, confusion, dizziness, irritability, headache, hunger, light-headedness, sweating, shaking, troublesleeping, feeling faint, extreme tiredness and weakness.The occurrence of reactive hypoglycemia is related to abnormal insulin secretion. Insulin secretion occurs inphases called the first and second phases. The first phase of insulin refers to the rapid release of ready insulin inthe first 10 minutes. Second phase insulin refers to the slowly released insulin over 24 hours. Loss of first-phaseinsulin secretion and decreased second-phase insulin secretion are characteristic features of type 2 diabetes. In theearly phase of type 2 diabetes and IGT, the first-phase insulin secretion declines. When the first-phase insulinresponse decreases, blood glucose starts to rise after the meal. This in turn, leads to late but excessive secretion ofthe second-phase insulin secretion and the mismatch leads to late reactive hypoglycemia.[2,3]

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